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Journal Club

The Promise of Stem Cell Research

stem cells


In fall 2013, the Natural Sciences Journal Club will focus on papers dealing with Stem Cells.

Upcoming Meetings:

The Natural Sciences Journal Club in now meeting each Thursday at 10:30 a.m. in Timken Science 251. 

Note: we have switched out meetings from Friday to Thursday.

At the remaining meeting this semester (11/7, 11/14, 11/21, & 12/5) we will be discussing Vascularized and functional human liver from an iPSC-derived organ bud transplant  by Takebe et al. that was published in the July 25, 2013 issue of Nature.

      If you have any questions, please contact Dr. Rogers at aebtref+znybar+rqh or Dr. Huisinga at xuhvfvatn+znybar+rqh or feel free to connect with us on the Natural Sciences Journal Club facebook page.

This semester we will be using information from the NIH stem cell website.  The excerpt below discusses some of the basic information about stem cells.

stem cell attacking hiv

What are stem cells, and why are they important?

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Second, under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.

 

Below are links to resources available to learn about stem cells.

prometheus         

NIH Regenerative Medicine

Takahashi and Yamanaka, 2006, Cell

Takahashi et al., 2007, Cell

Supplement to Takahashi et al., 2007

Nature News & Views on Liver Buds  

 

 



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